Cilia drop anchor

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Cilia drop anchor

Cilia hoist dust out of the lungs, propel sperm toward the egg, and enable us to catch the scent of fresh coffee. The structures also help some cells attach to their surroundings, Schouteden et al. reveal (1). A cilium is built around the axoneme, an internal shaft of microtubules that sprouts from a structure known as the basal body. Between the axoneme and the basal body lies the transition z...

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Leukocytes drop anchor

B urkart et al. describe how a secreted protease helps egg cells avoid being fertilized by more than one sperm. Because polyspermy disrupts em-bryonic development, oocytes take several steps to ensure they only fuse with a single sperm. One key step is to prevent additional sperm from binding to the surface of an already-fertilized egg, a blockade that involves the release of secretory granules...

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Primary cilia

The primary cilium was first so named by Sergei Sorokin in 1968.[1] Since the discovery of primary cilium in 1898 by Zimmerman, three major hypotheses for their function have been put forth. The first is that primary cilia are vestigial organelles inherited from an ancestor whose cells had motile cilia and now are of no purpose in multicellular organisms. The second is that they are involved in...

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Cilia graft.

Numerous aetiological factors can be involved in loss of eyelid substance and ideally, wherever possible, such deficits are closed by primary anastomosis. However, in the presence of extensive trauma, tumour formation, or congenital anomaly, a number of reconstructive techniques may have to be employed. These are outlined elsewhere (Smith, I959; Smith and English, 1970), but briefly to recapitu...

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Cilia signaling

Cilia signaling I t takes well-built cilia to send developmental signals on their way, show Tamara Caspary, Kathryn Anderson (Sloan-Kettering Institute, New York, NY), and Christine Larkins (Emory University, Atlanta, GA). Cilia that lack the correct internal architecture fail to transduce Hedgehog (Hh) signals correctly. Hh signaling is particularly well-characterized in the developing nervous...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2015

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.2101if